Breed Profiles

Selkirk Rex: The Cat in Sheep’s Clothing

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Lilac Selkirk Rex in profile
Image by Adrian from Pixabay

Random mutations are the genesis of some of the most interesting cat breeds, including the Selkirk Rex. There are several rex breeds, distinguished by their curly coats. The Selkirk Rex is sometimes called “the cat in sheep’s clothing” due to its particularly wooly appearance [6, 7]. This is a relatively new breed, and still uncommon [1-4], but they charm everyone they meet with their lovely curls and warm personalities.

Humble Origins

In 1987, a shelter cat in Montana, USA gave birth to a litter of kittens [1, 3, 4, 6, 7]. This would be an unremarkable event except that one of them had curly fur [1-4, 7]. The little blue-cream-and-white she-kitten came to the attention of a local Persian breeder named Jeri Newman, who got excited about the possibility of a new rexoid mutation [1-3, 6, 7]. Newman adopted the kitten and named her Miss DePesto because she was always pestering people for attention [7]! When Miss DePesto grew up, Newman bred her with one of the Persians, a black tom named PhotoFinish of Deekay [1-3, 7]. Three of their six kittens had curly hair [1-3, 7].

This showed that Miss DePesto’s mutation was a dominant trait–a cat would only need one copy of the mutation to have curly fur. The Devon Rex and Cornish Rex mutations are both recessive, requiring two copies, so Newman definitely had something new on her hands [3, 7]. She developed the Selkirk Rex breed from Miss Depesto’s bloodline, incorporating not only Persians but also British Shorthairs, American Shorthairs, and Exotic Shorthairs [1, 6]. The breed began to be recognized by cat fancy organizations in the early 1990s [4, 7].

Breed Characteristics

Appearance

The hair, of course, is the star attraction. Selkirk Rexes can occasionally be born with straight fur if they inherit a wild-type (non-mutant) allele from both parents, but this doesn’t happen often because the mutation has already become almost fixed in the population [5]. A trait becomes “fixed” in a population when all individuals have the same genetic makeup for it. So most Selkirk Rexes have curly coats, including curly whiskers, both of which are apparent at birth [1-7]. The coat texture can change somewhat during the first months of life and doesn’t reach it’s full potential until kittens are 8-10 months old, however [1]. Their adult coat is plush and has loose curls [1-4, 6, 7]. Unlike other rex breeds, Selkirk Rexes have a full coat with all three layers [4]. They may have short or long fur [1-4, 6, 7].

Close-up of Selkirk Rex coat – Image by Adrian from Pixabay

The mutation that causes Selkirk Rexes to have curls is in the KRT71 gene which is important for producing the protein keratin in the hair follicles [5]. Different mutations in this same gene cause the recessive rexoid mutation in Devon Rexes and the nearly-hairless condition of Sphynx cats [5].

Due to their ancestry among Persians and breeds with similar builds, Selkirk Rexes are stocky cats [1-4, 6, 7] with moderately shortened muzzles [1]. They come in all colors and patterns [1-4, 6, 7].

Personality

The Selkirk Rex is a friendly and affectionate cat that loves spending time with people [1, 2, 6, 7]. They are laid-back and relaxed, but they aren’t as like to be lap cats as Persians–these kitties like to play, too [2, 6, 7]! They are generally patient and tolerant, and they get along well with children, other pets, and strangers, as long as they are well-socialized [2, 6, 7]. These cats just want to be the life of the party! But a mellow party, please. Selkirk Rexes make good pets for families [2, 6]. They can get bored if left alone for very long or not played with regularly, so keep that in mind [6].

Selkirk Rex at Home

A Selkirk Rex doesn’t have too many special requirements, but that beautiful coat does need some attention. Loose hair can become caught in their curls and lead to mats [2]. However, too much grooming can make their coat frizzy [2, 6]. If you have curly or wavy hair of your own, you’ll be familiar with that problem. Combing their fur weekly with a wide-toothed comb is the best way to work out tangles and loose fur without making kitty’s hair stand on end [2, 6]. Some Selkirk Rexes need baths occasionally as [2, 6]. If this is the case for your cat, make sure you use a light shampoo that won’t weight down and flatten their curls [2, 3]. Ask a veterinarian, groomer, or breeder for recommendations. After a bath, towel dry your Selkirk Rex, then let their coat air dry [2].

Health Concerns

Selkirk Rexes are fairly healthy, like most breeds that originated with random-bred cats. However, there is a lot of Persian and other purebred cats in their ancestry, and they have inherited a propensity toward a few health problems from that side of the family [2, 6]. Selkirk Rexes are a bit prone to polycystic kidney disease (PKD), a genetic kidney disorder that kittens are born with which leads to kidney failure later in life [2, 6]. Fortunately, there is a screening test for PKD, and responsible breeders will make sure they do not breed cats who carry it [2].

The Selkirk Rex is also more likely to develop Hypertrophic Cardiomyopathy (HCM), the most common form of heart disease in cats [2, 6]. Hip dysplasia, which is common in Persians, can be a risk as well [2, 6].

Because Selkirk Rex is a new and still rare breed, they don’t often arrive in animal shelters, but it’s always better to adopt than shop. You might be surprised–lost and abandoned purebred cats go to shelters and rescues everyday. You can also look at places like Selkirk Rex Rescue & Retired Breeding Cats, where fanciers are trying to find good homes for their favorite breed.

Fun Facts

Gray Selkirk Rex in front of rainbow pillows
Image by Adrian from Pixabay
  • The Selkirk Rex is the only breed named after a real person. Jeri Newman chose the name “Selkirk” in honor of her stepfather. [6]
  • Sterilized mature Selkirk Rexes have the highest quality coats. [3, 7]
  • The birthplace of the Selkirk Rex, in the form of Miss DePesto, was the Bozeman Humane Society [1]. The area is now served by Heart of the Valley Animal Shelter.

Works Cited

  1. Alderton, D. (1992). Cats: The visual guide to more than 250 types of cats from around the world. Dorling Kindersley: London.
  2. Brown, J. (2022, July 14). Selkirk Rex: Cat breed profile, characteristics & care. The Spruce Pets. https://www.thesprucepets.com/selkirk-rex-cat-breed-profile-4774250
  3. Cat Fanciers’ Association. (n.d.). About the Selkirk Rex. https://cfa.org/selkirk-rex/
  4. Edwards, A. (2006). The ultimate encyclopedia of cat, cat breeds, and cat care. Hermes House: London.
  5. Gandolfi, B., Alhaddad, H., Joslin, S. E. K., Khan, R., et al. (2013). A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats. Scientific Reports, 3, 2000. https://doi.org/10.1038/srep02000
  6. Jimerson, G. and Guthrie, C. (2022, January 26). Selkirk Rex. The Daily Paws. https://www.dailypaws.com/cats-kittens/cat-breeds/selkirk-rex
  7. The International Cat Association. (2018, August 13). Selkirk Rex breed. https://www.tica.org/breeds/browse-all-breeds?view=article&id=875:selkirk-rex-breed&catid=79

Published January 8th, 2022

Updated June 14th, 2023

Science

Coat Length and Texture Genetics

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By special request from Emma S.

I am back with the genetics! A friend asked me if I was going to address the genetics of cat fur length in addition to my previous blogs on coat genetics. I wasn’t sure there was enough information to fill up a whole blog, but I dove in anyway. It turns out, there’s plenty. It’s not just the difference between a longhair and a shorthair, but also hairless cats and sort-of-hairless cats and curly-haired cats. Cats are complicated. Genetics is complicated. That’s kind of the fun of it, though. So, this one is for you, Emma. Enjoy.

Longhair ginger tabby cat in autumn woods
Long hair is recessive to short hair – Photo by Steven Iodice from Pixabay

Shorthair vs. Longhair

Let’s start with the basics. If you need a refresher on the principles of genetics, look over the first few paragraphs of my coat color genetics post. Ready? Let’s go. The wild-type, or default, fur for cats is short with no texture modifications. Long hair is recessive to short hair [1-4]. This has been common wisdom for a while, but genetic studies confirmed it in 2007 [1, 2].

The researchers discovered four mutations in the same gene, Fibroblast Growth Factor 5 (FGF5), which cause cats to have long fur [1, 2]. FGF5 mutations were already known to cause hair-length variability in mice and dogs at the time the studies were conducted, so this was not a surprising result [1, 2]. In studies with mice, the FGF5 protein signaled hair to exit the growth phase and enter the static phase [2]. When mutations in FGF5 cause the protein to be nonfunctional, the growth phase of the hair lasts longer [2]. Hence, longer fur.

The four FGF5 mutations in long-haired cats were, creatively, named Mutation 1-4 [2, 3]. Mutation 1 seems to be exclusive to Ragdoll cats [2]. Mutation 2 was only found in Norwegian Forest Cats [1, 2]. Maine Coons are most likely to have Mutation 3, but Ragdolls might as well [1, 2]. Mutation 4 belongs to all long-haired breeds and random-bred longhairs [1, 2]. So far, there is not indication that any gene besides FGF5 contributes to the longhair phenotype. The fact that at least four mutations in this gene exist, three of them breed-specific, suggests that the trait has arisen multiple times through a similar mechanism. This is probably because, in certain environments, long fur is advantageous. It has also sometimes been artificially selected for.

Now, we know that there are not just two lengths of cat fur, one long and one short. There are many variations within both the shorthair and longhair categories, and some cats are kind of in-between. This is because very few things are affected by just one gene. An unknown number of modifier genes determine the exact length of a cat’s hair relative to their genotype at the primary hair length locus [4].

Hairless, or Near Enough

Some cats or breeds are more or less hairless. True hairlessness is almost unheard of. Hairless cats present with a variety of traits that we call “hairless.” Most have very thin coats that look as if they aren’t there at all. Some have fur that thins drastically in only certain places. In either case, the degree of “hairlessness” can vary widely. As one would expect with so much natural variation, more than one mutation causes the different patterns of feline hairlessness. Sometimes the trait is dominant, and sometimes it is recessive [3, 4].

Four cream Sphynx kittens on blue cat bed
The Sphynx trait is caused by the hr mutation – Image by mjlovesmm from Pixabay

A recessive mutation dubbed hr gives the easily-identifiable Sphynx its hairless phenotype [3, 4, 5]. The Sphynx is a typical hairless breed with an extremely thin, downy coat that gives the appearance of baldness [5]. The hr allele is a mutation in the Keratin 71 (KRT71) gene [5]. The keratin 71 protein is expressed in the inner root sheath of the hair follicle and is important for the normal formation of the hair [5]. The hr mutation does not prevent hair from forming, but the hairs are easily dislodged because the hair bulbs are weak, resulting in the distinctive naked appearance of the Sphynx [5].

The Russian hairless breeds, Peterbald and Donskoy, carry the semi-dominant Hp mutation [4, 6]. Other genes affect how strongly the Hp hairlessness allele is expressed [4, 6]. The cats’ coats range from a brush coat–sparse, rigid, curly fur–to hairless all over [4]. Hairless mutations identified in British and French cats, hd and h respectively, are recessive [3, 4]. Sadly, hd is also a lethal mutation [4].

The Lykoi breed displays partial hairlessness. They have a thin coat all over and a hairless face, sometimes with other patches of hairless, especially on the legs. Lykoi molt all of their hair at least once in their life and may molt as often as every shedding season. This arguably makes them a breed that is truly hairless, albeit only for short periods of time. Six different mutations have been found to cause the Lykoi phenotype, but all of them are mutant alleles of the same gene, lysine demethylase and nuclear receptor corepressor, abbreviated HR for “hairless” [7]. Mutations in HR also cause hair abnormalities in humans, mice, sheep, and macaques [7].

Rexoid Variations

Curly fur occurs naturally in quite a few mammals, including dogs, rabbits, and cats. There are five recognized breeds of curly-coated cats, per the Cat Fanciers’ Association and The International Cat Association: American Wirehair, Cornish Rex, Devon Rex, LaPerm, and Selkirk Rex. Several other potential rexoid breeds have been proposed, including the German Rex and Oregon Rex. While all of these cats–and some random-bred cats–have curly coats, there are a lot of different causal mutations.

Remember the KRT71 gene? One kind of mutation in it causes the Sphynx’s hairlessness, but a different KRT71 mutation makes the Devon Rex’s pelt curly [5]. The Devon Rex mutant allele, re, is recessive to the wild-type allele but also to the hr Sphynx allele [5]. Devon Rex cats were used in the early Sphynx breeding programs, so some Sphynx still have one hr and one re allele, but they look just like any other Sphynx [5].

Lilac cat with curly fur on wood table
Selkirk Rexes can have long or short hair – Image by athree23 from Pixabay

A recessive mutation also causes the Cornish Rex’s curly coat, but in their case the gene in question is lysophosphatidic acid receptor 6 (LPAR6) [8]. The mutant allele, known as r, causes the Cornish Rex to only develop an undercoat, one of the three layers of a normal pelt, and a curly one at that [8, 9]. Humans who are homozygous for LPAR6 mutations have a similar phenotype known as “wooly hair” [8]. Because the Cornish Rex was used to found the German Rex, r is in the genetic background of German Rexes, too [8].

Unlike the Devon and Cornish, the Selkirk Rex mutation, Se, is dominant, although incompletely dominant [9]. This means that cats homozygous for the mutation have a more dramatic phenotype: thinner coats, tighter curls [9]. And, wouldn’t you know it, Se is an unique mutation of our old friend, KRT71 [10]. Both KRT71 and LPAR6 are genes that maintain normal hair growth [5, 8]. It makes sense that different mutations in the same or similar genes would cause similar results.

Works Cited

  1. Drögemüller, C., Rüfenacht, S., Wichert, B., and Leeb, T. (2007). Mutations within the FGF5 gene are associated with hair length in cats. Animal Genetics, 38(3), 218-221. https://doi.org/10.1111/j.1365-2052.2007.01590.x
  2. Kehler, J.S., David, V.A., Schäffer, A.A., Bajema, K., et al. (2007). Four independent mutations in the feline Fibroblast Growth Factor 5 gene determine the long-haired phenotype in domestic cats. Journal of Heredity, 98(6), 555-566. https://doi.org/10.1093/jhered/esm072
  3. Basepaws. (2019, July 14). Cat coat genetics. Basepaws, Inc. https://www.basepaws.com/blog/cat-coat-genetics/
  4. Hartwell, S. (n.d.) Genetics of colour and conformation. MessyBeast. http://messybeast.com/cat-genetics-basics.htm
  5. Gandolfi, B., Outerbridge, C.A., Beresford, L.G., Myers, J.A., et al. (2010). The naked truth: Sphynx and Devon Rex cat breed mutations in KRT71. Mammalian Genome, 21, 509-515. https://doi.org/10.1007/s00335-010-9290-6
  6. Zhigachev, A.I., Vladimirova, M.V., and Katser, I. (2000). Phenotypic and genotypic characteristics of Russian hairless cats. Genetika, 36(4), 538-544. https://europepmc.org/article/med/10822817
  7. Buckley, R.M., Gandolfi, B., Creighton, E.K., Pyne, C.A., et al. (2020). Werewolf, there wolf: variants in Hairless associated with hypotrichia and roaning in the lykoi cat breed. Genes, 11(6), 682. https://doi.org/10.3390/genes11060682
  8. Gandolfi, B., Alhaddad, H., Affolter, V.K., Brockman, J., et al. (2013). To the root of the curl: A signature of a recent selective sweep identifies a mutation that defines the Cornish Rex cat breed. PloS One, 8(6), e67105. https://doi.org/10.1371/journal.pone.0067105
  9. Basepaws. (2019, July 15). Curly cat coat: A special kind of eye candy. Basepaws, Inc. https://www.basepaws.com/blog/curly-cat-coat/
  10. Gandolfi, B., Alhaddad, H., Joslin, S.E.K., Khan, R., et al. (2013). A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats. Scientific Reports 3, 2000. https://doi.org/10.1038/srep02000

Published November 1st, 2020

Updated June 14th, 2023

Breed Profiles

Cornish Rex: Curly Cats Fit for a King

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White and gray cat on blanket
Image by duodenum82 from Pixabay

Cornwall, England is said to be the birthplace of King Arthur, but it was also the birthplace of a truly unique breed of cat. The Cornish Rex was the first of the rexes, a group of cat breeds with an unusual curly or wavy coat. This foundational breed was named for its place of origin and its resemblance to Astrex or Rex rabbits, which have a similar coat. “Rex” is Latin for king. Fitting, then, that a legendary king and a kingly cat call the same place home.

History

On July 21st, 1950, a calico barn cat named Selena gave birth to a litter of five kittens. Selena’s owner, Nina Ennismore, noticed something unusual about one of the kittens. The bat-eared, cream tom had a soft, curly coat unlike anything Ennismore had ever seen before in a cat, but as a former rabbit fancier, she had seen something similar and recognized the potential. She named the unusual kitten Kallibunker and got in touch with British geneticist A. C. Jude to ask for advice. Jude suggested mating Kallibunker to Selena (known as a backcross in genetic parlance). The first litter produced one kitten with a normal coat and two with curly coats like Kallibunker.

Breeding the newly-minted Cornish Rexes with Siamese, Burmese, and British Shorthairs to widen the gene pool always resulted in cats with normal coats. It was realized that the curly-coat trait is recessive. Kittens must inherit it from both parents. A 2013 study determined that the Cornish Rex mutation is a small deletion in the lysophosphatidic acid receptor 6 (LPAR6) gene, which is important for normal hair shaft development in mammals, including humans (1). Mutations in this gene in humans cause woolly hair syndromes or hypotrichosis (short or sparse hair) (1).

Brown rabbit sitting
Rex rabbit – Image by Vicky Prince from Pixabay

A pair of Cornish Rexes from Kallibunker’s family line were exported to the United States in 1957, where Russian Blues, Havana Browns, and American Shorthairs contributed to the breed as well. The journey to the States was fortunate for the breed’s longevity, as it nearly went extinct in the United Kingdom around the same time (2, 3). The Cornish Rex has made a comeback, however, and was the sixth most popular breed in the Cat Fanciers’ Association in 2019.

Breed Characteristics

Of course, the hallmark of the Cornish Rex is that unique coat. Most cats have three types/layers of hair. On the outside are tough, protective “guard hairs,” about 2 inches or 5 centimetres long on shorthairs and 4+ inches or 10+ centimetres on longhairs (4). In the middle is the “awn hair,” and then the “down hair” or undercoat made of very fine, soft hairs about 0.4 inches or 1 centimetre long (4). Cornish Rexes only have an undercoat, and what fur they do have is wavy or curly. Even their whiskers are curly! The texture of a their coat is sometimes compared to crushed velvet, silk, or, ironically, rabbit fur. Because of the diverse background of the breed, the coat can come in any color or pattern.

The shape of a Cornish Rex is an unique as their coat. They have a slender, arched body with long, delicate legs and small paws. Their waists are small but their thighs are muscular. In fact, despite their dainty appearance, they are generally quite muscular, athletic cats. They only look fragile. They are actually a medium-sized cat, weighing about eight pounds. The tail is long, thin, and tapering. The head is perhaps the most outstanding feature. It is egg-shaped with large, oval eyes, high cheekbones, and a Roman nose. The ears are gigantic and high on the head.

If you find those over-sized ears a little comical, it’s okay to laugh, because Cornish Rexes are known for their sense of humor and love of attention. They are very active, playful, and social cats who always want to be involved in what their people are doing. Cornish Rexes like to snuggle, but not for too long, as these cats are energetic and not usually interested in spending a lot of time laying in your lap. They typically get along with children and other pets. In fact, due to their friendliness and willingness to be handled, Cornish Rexes make good therapy cats (5, 6, 7). They do not do well being left alone for long periods of time, however. They are highly social. Since most of us aren’t home all day, it’s a good idea to have an animal friend if you want a Cornish Rex.

As with any breed, a Cornish Rex is not for everyone. Some people may find their desire to be up close and personal all the time irritating rather than charming. They might be too high-energy for some households. Cornish Rexes can be talkers, probably due to their Siamese ancestry. They are not as loud or as chatty as a Siamese, but they are known to like to hold a conversation once in a while, so if a quiet cat is your preference, then a Cornish Rex might not be a good choice. However, they are great cats for chaotic households (lots of kids, other animals, clients in and out, etc.). They also travel well, so if you want a cat that can go with you on your globetrotting lifestyle, this breed can be a great option.

Health and Care

Despite the early inbreeding, the Cornish Rex has benefited from outcrosses with many breeds. They are a fairly healthy breed with few genetic health risks. There is a somewhat elevated risk in their gene pool of hypertrophic cardiomyopathy, a common form of heart disease in cats. They are sometimes prone to patellar luxation, a condition where the kneecap moves out of place. This may be reparable. Cornish Rex sometimes have hypotrichosis, possibly resulting in bald spots. Bald spots may also be the result of over-grooming because of stress or anxiety, so check with a veterinarian.

Sometimes Cornish Rexes develop skin problems since they lack most of their protective fur. They are particularly prone to sunburn, especially if they have light or white fur. But they are also more likely to feel cold, so if you choose a Cornish Rex, be careful not to let it spend too much time basking in the sun. It may be necessary to apply cat-safe sunscreen, especially if you want to walk your cat or let them into your yard or onto a catio.

Cornish Rex can be sensitive to certain anesthetics and may experiences dangerous side effects (4). If you have one that needs a procedure, be sure to discuss this with your veterinarian.

When it comes to grooming, less may be more. Brushing a Cornish Rex may damage their delicate fur. However, they may have a buildup of oils because they have less fur to absorb them. Depending upon the cat, they may only need a little cleaning around the face and paws, or they may need regular baths. Watch inside the ears and on the claws for oily buildup as well.

Calico cat with curly fur
Photo by Nickolas Titkov from Wikimedia Commons

There is a myth that Cornish Rex are hypoallergenic because they have less hair than most cats. This is not true. Cat allergies are caused by proteins in cat danger and saliva, not by the hair itself. The hair can cause the offending dander to travel farther, and Cornish Rex do shed less, so some people with cat allergies might have less of a reaction to Cornish Rexes than other cats, but there is no guarantee. Rather than get a cat and find out it doesn’t help the allergies, and now you need to re-home it, it is best for someone with cat allergies to hand a cat of a breed they think might be less allergenic first and test their hypothesis.

If you think a Cornish Rex is the cat for you, adopt, don’t shop. Even purebred cats are surrendered every day. Check with your local shelter or see if there is a breed-specific rescue group in your area.

Fun Facts

  • The term “Rex” was first applied to curly fur at a rabbit show where King Albert I of Belgium (1875-1934) entered his curly-haired rabbits. The officials knew they didn’t meet the standards, but they dared not reject the king’s rabbits, so they accepted them but wrote “Rex” for “King” on the score sheets (4, 8).
  • Life magazine ran an article about Kallibunker in 1956. Quite the step up for a son-of-a-barn cat (3).
  • The same mutation that causes the Cornish Rex’s special coat is also found in the rare, lesser-known German Rex, but not in other Rex cat breeds (1).
  • Cornish Rexes have very dexterous paws. They pick up toys and throw them up in the air for their own entertainment. They’re happy to play catch with others, too.

Works Cited

  1. Gandolfi, B., et al. (2013). To the root of the curl: A signature of a recent selective sweep identifies a mutation that defines the Cornish Rex cat breed. PLoS One 8(6), e67105. https://doi.org/10.1371/journal.pone.0067105
  2. Puisis, E. (2019, July 25). Cornish Rex: Cat breed profile. The Spruce Pets. https://www.thesprucepets.com/learn-all-about-the-cornish-rex-cat-4694497
  3. Cat Fanciers’ Association. (n.d.). The Cornish Rex. https://cfa.org/cornish-rex/cornish-rex-article/
  4. Europetnet. (n.d.). Cornish Rex. https://www.europetnet.com/pet-resources/cat-breeds/item/1920-cornish-rex.html
  5. VetStreet. (n.d.). Cornish Rex. http://www.vetstreet.com/cats/cornish-rex#overview
  6. CatTime. (n.d.). Cornish Rex. https://cattime.com/cat-breeds/cornish-rex-cats#/slide/1
  7. Kelley, J. A. (2015, February 3). Get to know the Cornish Rex: A pack of personality in a ballet dancer’s body. Catster. https://www.catster.com/lifestyle/cat-breeds-cornish-rex-personality-ballet-dancer-body-pictures-photos
  8. Houle, T. (2014, December 16). The Cornish Rex. Pet Health Network. http://www.pethealthnetwork.com/cat-health/cat-breeds/cornish-rex
  9. Petfinder. (n.d.). Cornish Rex. https://www.petfinder.com/cat-breeds/cornish-rex/
  10. Cat Fanciers’ Association. (n.d.). About the Cornish Rex. https://cfa.org/cornish-rex/

Published August 30th, 2020

Updated October 15th, 2020